Research workbench

2.55 ångström resolution crystal structure of N-terminal fragment (residues 1-493) of DNA topoisomerase IV subunit a from pseudomonas putida

Analyse 2.55 ångström resolution crystal structure of N-terminal fragment (residues… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6BQ9
Type: protein
Length: 457 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA topoisomerase 4 subunit a
EC: 5.99.1.3
UniProt: Q88DB5
Ligands: NA, CL
Pockets: 6 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA topoisomerase 4 subunit a (EC 5.99.1.3)	protein	457	46% helix, 16% strand	Q88DB5

Ligands and binding sites

NA · Sodium ion · metal · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	314	0.64	0.80	46	NA
2	187	0.52	0.78	36	CL
3	57	0.45	0.83	14	empty
4	89	0.36	0.75	12	empty
5	54	0.35	0.79	14	empty

Compared structures

6BQ9 · 2.55 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-493) of DNA… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q88DB5
Elsewhere: RCSB PDB 6BQ9 · PDBe 6BQ9 · UniProt Q88DB5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.