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Recombinant major vault protein [rattus norvegicus] structure in solution: conformation 2

Analyse Recombinant major vault protein [rattus norvegicus] structure in solution… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6BP7
Type
protein
Length
772 residues
Chains
1
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Major vault protein
UniProt
Q62667
Pockets
5 · best druggability 0.60

Structure

electron microscopy · 1 distinct chain · 27% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMajor vault proteinprotein77227% helix, 25% strandQ62667

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11780.600.8231empty
21580.490.7823empty
31370.430.7626empty
4960.420.7817empty
5690.360.7716empty

Compared structures

  • 6BP7 · Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q62667 · AlphaFold monomer V2.0 prediction for major vault protein (Q62667) · a predicted model of the same protein · chain A against A, TM-score 0.72

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