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Crystal structure of native fused 4-ot

Analyse Crystal structure of native fused 4-ot in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6BLM
Type: protein
Length: 381 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 4-oxalocrotonate tautomerase
UniProt: Q392K7
Pockets: 5 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	4-oxalocrotonate tautomerase	protein	127	39% helix, 30% strand	Q392K7

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.72	0.97	27	empty
2	203	0.52	0.77	33	empty
3	111	0.42	0.77	18	empty
4	68	0.30	0.74	18	empty
5	51	0.28	0.75	17	empty

Interfaces

3 interfaces between chains.

A–C · 1343 Å² buried · 20 hydrogen bonds · protein-protein
A–B · 1335 Å² buried · 25 hydrogen bonds · protein-protein
B–C · 1313 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

6BLM · Crystal Structure of Native Fused 4-OT · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q392K7
Elsewhere: RCSB PDB 6BLM · PDBe 6BLM · UniProt Q392K7

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