Research workbench
Human ABO(H) blood group glycosyltransferase gtb R188K mutant
Analyse Human ABO(H) blood group glycosyltransferase gtb R188K mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6BJM
- Type
- protein
- Length
- 277 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Abo blood group (transferase a, alpha 1-3-N- acetylgalactosaminyltransferase transferase…
- UniProt
- D3HIC2
- Pockets
- 2 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Abo blood group (transferase a, alpha 1-3-N- acetylgalactosaminyltransferase transferase B, alpha 1-3- galactosyltransferase) | protein | 277 | 32% helix, 20% strand | D3HIC2 |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 303 | 0.56 | 0.76 | 29 | GOL |
| 2 | 54 | 0.26 | 0.72 | 12 | empty |
Compared structures
- 6BJM · Human ABO(H) blood group glycosyltransferase GTB R188K mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D3HIC2
- Elsewhere: RCSB PDB 6BJM · PDBe 6BJM · UniProt D3HIC2
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