Research workbench
Calcium-independent phospholipase A2 beta
Analyse Calcium-independent phospholipase A2 beta in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6AUN
- Type
- protein
- Length
- 1,236 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PLA2G6, IPLA2BETA
- EC
- 3.1.1.4
- Pockets
- 19 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | PLA2G6, IPLA2BETA (EC 3.1.1.4) | protein | 618 | 42% helix, 6% strand | — |
Pockets
19 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 514 | 0.85 | 0.91 | 72 | empty |
| 2 | 272 | 0.77 | 0.90 | 41 | empty |
| 3 | 62 | 0.73 | 0.98 | 18 | empty |
| 4 | 130 | 0.67 | 0.89 | 32 | empty |
| 5 | 195 | 0.63 | 0.83 | 34 | empty |
Interfaces
1 interface between chains.
- A–B · 2836 Ų buried · 30 hydrogen bonds · protein-protein
Compared structures
- 6AUN · calcium-independent phospholipase A2 beta · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6AUN · PDBe 6AUN
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