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Structure of a thermostable group II intron reverse transcriptase with template-primer and its functional and evolutionary implications (duplex only)

Analyse Structure of a thermostable group II intron reverse transcriptase with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6AR5
Type
DNA + RNA
Length
27 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA; RNA
Pockets
1 · best druggability 0.37

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNAdna13——
BRNArna14——

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11680.370.7221empty

Interfaces

1 interface between chains.

  • A–B · 618 Ų buried · 70 hydrogen bonds · nucleic-nucleic

Compared structures

  • 6AR5 · Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer… · the same entry in another collection · chain A against A, TM-score 1.00

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