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Crystal structure of unoccupied murine upar

Analyse Crystal structure of unoccupied murine upar in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6AEX
Type: protein
Length: 165 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Urokinase plasminogen activator surface receptor
UniProt: P35456
Ligands: NAG
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
U	Urokinase plasminogen activator surface receptor	protein	165	5% helix, 45% strand	P35456

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains U

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.46	0.82	16	empty

Modifications

Observed in the structure: 10 disulfide, 1 glycan (disulfide, glycosylation).

Compared structures

6AEX · Crystal structure of unoccupied murine uPAR · the same entry in another collection · chain U against U, TM-score 1.00
P35456 · AlphaFold monomer V2.0 prediction for urokinase plasminogen activator surface receptor… · a predicted model of the same protein · chain U against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35456
Elsewhere: RCSB PDB 6AEX · PDBe 6AEX · UniProt P35456

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