Research workbench
Crystal structure of CSM2 of the type III-a CRISPR-CAS effector complex
Analyse Crystal structure of CSM2 of the type III-a CRISPR-CAS effector complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6AE1
- Type
- protein
- Length
- 228 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CRISPR-associated protein, TM1810 family
- UniProt
- Q5HK90
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 76% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | CRISPR-associated protein, TM1810 family | protein | 114 | 76% helix, 4% strand | Q5HK90 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.40 | 0.76 | 16 | empty |
| 2 | 91 | 0.37 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 638 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 6AE1 · Crystal structure of Csm2 of the type III-A CRISPR-Cas effector complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5HK90
- Elsewhere: RCSB PDB 6AE1 · PDBe 6AE1 · UniProt Q5HK90
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.