Research workbench
Structural characterization of the condensation domain from monacolin K polyketide synthase moka
Analyse Structural characterization of the condensation domain from monacolin K… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6AD3
- Type
- protein
- Length
- 450 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lovastatin nonaketide synthase moka
- EC
- 2.3.1.161
- UniProt
- Q3S2T9
- Pockets
- 5 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lovastatin nonaketide synthase moka (EC 2.3.1.161) | protein | 450 | 38% helix, 22% strand | Q3S2T9 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 832 | 0.83 | 0.86 | 95 | empty |
| 2 | 101 | 0.41 | 0.77 | 19 | empty |
| 3 | 75 | 0.37 | 0.77 | 15 | empty |
| 4 | 52 | 0.34 | 0.78 | 13 | empty |
| 5 | 52 | 0.28 | 0.75 | 16 | empty |
Compared structures
- 6AD3 · Structural characterization of the condensation domain from Monacolin K polyketide… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3S2T9
- Elsewhere: RCSB PDB 6AD3 · PDBe 6AD3 · UniProt Q3S2T9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.