Research workbench
Actin interacting protein 5 (AIP5, mutant)
Analyse Actin interacting protein 5 (AIP5, mutant) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ABS
- Type
- protein
- Length
- 193 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Actin binding protein
- UniProt
- P43597
- Pockets
- 2 · best druggability 0.52
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Actin binding protein | protein | 98 | 47% helix, 18% strand | P43597 |
| B | Actin binding protein | protein | 95 | 47% helix, 19% strand | P43597 |
Ligands and binding sites
- PGE · Triethylene glycol · additive · chains A, B
- 1PE · Pentaethylene glycol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 215 | 0.52 | 0.77 | 25 | 1PE |
| 2 | 56 | 0.40 | 0.81 | 13 | PGE |
Interfaces
1 interface between chains.
- A–B · 400 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43597
- Elsewhere: RCSB PDB 6ABS · PDBe 6ABS · UniProt P43597
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