Research workbench

Actin interacting protein 5 (AIP5, wild type)

Analyse Actin interacting protein 5 (AIP5, wild type) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6ABR
Type: protein
Length: 181 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Actin binding protein
UniProt: P43597
Pockets: 1 · best druggability 0.51

Structure

x-ray diffraction · 2 distinct chains · 36% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Actin binding protein	protein	96	38% helix, 19% strand	P43597
B	Actin binding protein	protein	85	35% helix, 21% strand	P43597

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	278	0.51	0.75	37	empty

Interfaces

1 interface between chains.

A–B · 300 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

6ABR · Actin interacting protein 5 (Aip5, wild type) · the same entry in another collection · chain B against B, TM-score 1.00
P43597 · AlphaFold monomer V2.0 prediction for uncharacterized protein YFR016C (P43597) · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P43597
Elsewhere: RCSB PDB 6ABR · PDBe 6ABR · UniProt P43597

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