Research workbench
Open reading frame 49
Analyse Open reading frame 49 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6A4V
- Type
- protein
- Length
- 539 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 49 protein
- UniProt
- P88987
- Pockets
- 7 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 49 protein | protein | 269 | 75% helix, 2% strand | P88987 |
| B | 49 protein | protein | 270 | 76% helix, 2% strand | P88987 |
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 183 | 0.78 | 0.93 | 27 | empty |
| 2 | 241 | 0.77 | 0.90 | 28 | empty |
| 3 | 479 | 0.67 | 0.79 | 50 | empty |
| 4 | 50 | 0.55 | 0.90 | 13 | empty |
| 5 | 63 | 0.53 | 0.87 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1821 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 6A4V · Open Reading frame 49 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P88987
- Elsewhere: RCSB PDB 6A4V · PDBe 6A4V · UniProt P88987
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