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Crystal structure of wheat glutarredoxin

Analyse Crystal structure of wheat glutarredoxin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5ZVL
Type: protein
Length: 527 residues
Chains: 5
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutaredoxin
UniProt: B5A8A6
Pockets: 3 · best druggability 0.33

Structure

x-ray diffraction · 4 distinct chains · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutaredoxin	protein	104	47% helix, 16% strand	B5A8A6
B	Glutaredoxin	protein	108	48% helix, 15% strand	B5A8A6
C, D	Glutaredoxin	protein	106	46% helix, 17% strand	B5A8A6
E	Glutaredoxin	protein	103	42% helix, 17% strand	B5A8A6

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.33	0.73	19	empty
2	71	0.32	0.75	13	empty
3	74	0.31	0.74	17	empty

Interfaces

4 interfaces between chains.

A–B · 363 Å² buried · 1 hydrogen bond · protein-protein
C–D · 359 Å² buried · 0 hydrogen bonds · protein-protein
D–E · 339 Å² buried · 0 hydrogen bonds · protein-protein
B–C · 337 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5ZVL · Crystal Structure of Wheat Glutarredoxin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B5A8A6
Elsewhere: RCSB PDB 5ZVL · PDBe 5ZVL · UniProt B5A8A6

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