Research workbench
Crystal structure of HSP104 from chaetomium thermophilum
Analyse Crystal structure of HSP104 from chaetomium thermophilum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5ZUI
- Type
- protein
- Length
- 686 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock protein 104
- Ligands
- ADP, SO4
- Pockets
- 10 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 57% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock protein 104 | protein | 686 | 57% helix, 12% strand | — |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains A
- SO4 · Sulfate ion · ion · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.67 | 0.84 | 38 | empty |
| 2 | 78 | 0.65 | 0.91 | 20 | empty |
| 3 | 350 | 0.64 | 0.79 | 38 | empty |
| 4 | 372 | 0.60 | 0.77 | 31 | ADP, SO4 |
| 5 | 191 | 0.53 | 0.78 | 28 | ADP |
Compared structures
- 5ZUI · Crystal Structure of HSP104 from Chaetomium thermophilum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5ZUI · PDBe 5ZUI
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