Research workbench
Proteobacterial origin of protein arginine methylation and regulation of complex I assembly by mida
Analyse Proteobacterial origin of protein arginine methylation and regulation of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5ZTZ
- Type
- protein
- Length
- 1,203 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial
- EC
- 2.1.1.320
- UniProt
- Q54S83
- Pockets
- 12 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial (EC 2.1.1.320) | protein | 401 | 36% helix, 22% strand | Q54S83 |
Pockets
12 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 718 | 0.79 | 0.83 | 58 | empty |
| 2 | 600 | 0.77 | 0.83 | 63 | empty |
| 3 | 829 | 0.76 | 0.80 | 58 | empty |
| 4 | 52 | 0.71 | 0.99 | 19 | empty |
| 5 | 52 | 0.71 | 0.98 | 20 | empty |
Interfaces
2 interfaces between chains.
- A–C · 819 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 818 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 33 modified (engineered).
Compared structures
- 5ZTZ · Proteobacterial origin of protein arginine methylation and regulation of Complex I… · the same entry in another collection · chain A against A, TM-score 1.00
- Q54S83 · AlphaFold monomer V2.0 prediction for protein arginine methyltransferase NDUFAF7 homolog… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q54S83
- Elsewhere: RCSB PDB 5ZTZ · PDBe 5ZTZ · UniProt Q54S83
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