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Crystal structure of N-terminal domain of plasmodium falciparum P43

Analyse Crystal structure of N-terminal domain of plasmodium falciparum P43 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5ZKH
Type: protein
Length: 328 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43
UniProt: A0A0L7M8L6
Pockets: 5 · best druggability 0.54

Structure

x-ray diffraction · 2 distinct chains · 52% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43	protein	160	53% helix, 10% strand	A0A0L7M8L6
B	Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43	protein	168	52% helix, 9% strand	A0A0L7M8L6

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.54	0.84	25	empty
2	61	0.46	0.83	16	empty
3	72	0.38	0.78	17	empty
4	61	0.36	0.77	16	empty
5	79	0.32	0.74	18	empty

Interfaces

1 interface between chains.

A–B · 848 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

5ZKH · Crystal Structure of N-terminal Domain of Plasmodium falciparum p43 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0L7M8L6
Elsewhere: RCSB PDB 5ZKH · PDBe 5ZKH · UniProt A0A0L7M8L6

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