Research workbench
Textilinin-1, a kunitz-type serine protease inhibitor from pichia expression system
Analyse Textilinin-1, a kunitz-type serine protease inhibitor from pichia expression… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5ZJ3
- Type
- protein
- Length
- 170 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kunitz-type serine protease inhibitor textilinin-1
- UniProt
- Q90WA1
- Pockets
- 1 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 21% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Kunitz-type serine protease inhibitor textilinin-1 | protein | 56 | 21% helix, 27% strand | Q90WA1 |
| B | Kunitz-type serine protease inhibitor textilinin-1 | protein | 58 | 21% helix, 28% strand | Q90WA1 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 494 | 0.70 | 0.80 | 51 | empty |
Interfaces
3 interfaces between chains.
- A–B · 668 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 250 Ų buried · 4 hydrogen bonds · protein-protein
- B–C · 195 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 5ZJ3 · Textilinin-1, A Kunitz-Type Serine Protease Inhibitor From pichia expression system · the same entry in another collection · chain A against A, TM-score 1.00
- Q90WA1 · AlphaFold monomer V2.0 prediction for kunitz-type serine protease inhibitor textilinin-1… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q90WA1
- Elsewhere: RCSB PDB 5ZJ3 · PDBe 5ZJ3 · UniProt Q90WA1
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