Crystal structure of hexacoordinated heme protein from anhydrobiotic tardigrade at pH 4

Structure

x-ray diffraction · 2 distinct chains · 80% helix, 0% strand (DSSP).

Ligands and binding sites

• HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains A, B, C, D
• SO4 · Sulfate ion · ion · 7 copies · chains A, C, B
• EDO · 1,2-ethanediol · additive · 3 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Interfaces

5 interfaces between chains.

• A–B · 851 Ų buried · 19 hydrogen bonds · protein-protein
• C–D · 824 Ų buried · 18 hydrogen bonds · protein-protein
• B–C · 340 Ų buried · 12 hydrogen bonds · protein-protein
• A–D · 282 Ų buried · 2 hydrogen bonds · protein-protein
• A–C · 275 Ų buried · 2 hydrogen bonds · protein-protein

Compared structures

• 5ZIQ · Crystal structure of hexacoordinated heme protein from anhydrobiotic tardigrade at pH 4 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A1D1V896
• Elsewhere: RCSB PDB 5ZIQ · PDBe 5ZIQ · UniProt A0A1D1V896