Research workbench
Trimeric structure of vibrio cholerae heat shock protein 15 at 2.3 ångström resolution
Analyse Trimeric structure of vibrio cholerae heat shock protein 15 at 2.3 ångström… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5Z81
- Type
- protein
- Length
- 297 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock protein 15
- UniProt
- A0A0H3AM46
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Heat shock protein 15 | protein | 99 | 35% helix, 21% strand | A0A0H3AM46 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 3 copies · chains A, B, C
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 3 copies · chains A, C, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 516 | 0.69 | 0.79 | 77 | empty |
| 2 | 268 | 0.55 | 0.76 | 20 | empty |
| 3 | 51 | 0.29 | 0.76 | 15 | empty |
Interfaces
3 interfaces between chains.
- A–B · 536 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 524 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 495 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 5Z81 · Trimeric structure of Vibrio cholerae Heat Shock Protein 15 at 2.3 Angstrom resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3AM46
- Elsewhere: RCSB PDB 5Z81 · PDBe 5Z81 · UniProt A0A0H3AM46
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