Research workbench
Crystal structure of pacysb regulatory domain
Analyse Crystal structure of pacysb regulatory domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5Z50
- Type
- protein
- Length
- 464 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cys regulon transcriptional activator
- UniProt
- O05926
- Ligands
- SO4
- Pockets
- 6 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cys regulon transcriptional activator | protein | 232 | 37% helix, 26% strand | O05926 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 185 | 0.74 | 0.90 | 38 | SO4 |
| 2 | 185 | 0.49 | 0.76 | 28 | SO4 |
| 3 | 170 | 0.45 | 0.75 | 28 | SO4 |
| 4 | 90 | 0.32 | 0.73 | 13 | empty |
| 5 | 59 | 0.29 | 0.74 | 15 | GOL |
Interfaces
1 interface between chains.
- A–B · 1215 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 5Z50 · Crystal structure of PaCysB regulatory domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O05926
- Elsewhere: RCSB PDB 5Z50 · PDBe 5Z50 · UniProt O05926
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