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Crystal structure of the kelch domain of human NS1-bp

Analyse Crystal structure of the kelch domain of human NS1-bp in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5YY8
Type: protein
Length: 284 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Influenza virus NS1A-binding protein
UniProt: Q9Y6Y0
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Influenza virus NS1A-binding protein	protein	284	1% helix, 50% strand	Q9Y6Y0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	360	0.74	0.85	36	empty

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

5YY8 · Crystal structure of the Kelch domain of human NS1-BP · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y6Y0 · AlphaFold monomer V2.0 prediction for influenza virus NS1A-binding protein (Q9Y6Y0) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y6Y0
Elsewhere: RCSB PDB 5YY8 · PDBe 5YY8 · UniProt Q9Y6Y0

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