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Solution structure of the DISC1/NDEL1 complex

Analyse Solution structure of the DISC1/NDEL1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5YI4
Type: protein
Length: 145 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Disrupted in schizophrenia 1 HOMOLOG,NUCLEAR distribution protein nude-like 1
UniProt: Q811T9, Q9ERR1
Pockets: 1 · best druggability 0.39

Structure

solution nmr · 1 distinct chain · 59% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Disrupted in schizophrenia 1 HOMOLOG,NUCLEAR distribution protein nude-like 1	protein	145	59% helix, 1% strand	Q811T9, Q9ERR1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	134	0.39	0.74	28	empty

Compared structures

5YI4 · Solution Structure of the DISC1/Ndel1 complex · the same entry in another collection · chain A against A, TM-score 1.00
Q811T9 · AlphaFold monomer V2.0 prediction for disrupted in schizophrenia 1 homolog (Q811T9) · a predicted model of the same protein · chain A against A, TM-score 0.51
Q9ERR1 · AlphaFold monomer V2.0 prediction for nuclear distribution protein nude-like 1 (Q9ERR1) · a predicted model of the same protein · chain A against A, TM-score 0.32

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q811T9
Every structure of UniProt Q9ERR1
Elsewhere: RCSB PDB 5YI4 · PDBe 5YI4 · UniProt Q811T9 · UniProt Q9ERR1

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