Research workbench
Crystal structure of the flexible tandem repeat domain of bacterial cellulose synthase subunit C
Analyse Crystal structure of the flexible tandem repeat domain of bacterial cellulose… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5XW7
- Type
- protein
- Length
- 1,146 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cellulose synthase subunit C
- UniProt
- K0J1W8
- Pockets
- 11 · best druggability 0.79
Structure
x-ray diffraction · 5 distinct chains · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cellulose synthase subunit C | protein | 243 | 74% helix, 0% strand | K0J1W8 |
| B | Cellulose synthase subunit C | protein | 218 | 75% helix, 0% strand | K0J1W8 |
| C | Cellulose synthase subunit C | protein | 245 | 72% helix, 0% strand | K0J1W8 |
| D | Cellulose synthase subunit C | protein | 241 | 73% helix, 0% strand | K0J1W8 |
| E | Cellulose synthase subunit C | protein | 199 | 76% helix, 0% strand | K0J1W8 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1017 | 0.79 | 0.80 | 104 | empty |
| 2 | 952 | 0.78 | 0.80 | 81 | empty |
| 3 | 302 | 0.66 | 0.82 | 41 | empty |
| 4 | 147 | 0.57 | 0.82 | 22 | empty |
| 5 | 148 | 0.55 | 0.81 | 27 | empty |
Interfaces
8 interfaces between chains.
- A–B · 1364 Ų buried · 15 hydrogen bonds · protein-protein
- C–D · 1245 Ų buried · 16 hydrogen bonds · protein-protein
- B–D · 527 Ų buried · 2 hydrogen bonds · protein-protein
- D–E · 513 Ų buried · 1 hydrogen bond · protein-protein
- B–E · 389 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5XW7 · Crystal structure of the flexible tandem repeat domain of bacterial cellulose synthase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt K0J1W8
- Elsewhere: RCSB PDB 5XW7 · PDBe 5XW7 · UniProt K0J1W8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.