Research workbench
Bacterial luciferase
Analyse Bacterial luciferase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1LUC
- Type
- protein
- Length
- 646 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bacterial luciferase
- EC
- 1.14.14.3
- UniProt
- P07740, P07739
- Ligands
- MG
- Pockets
- 9 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bacterial luciferase (EC 1.14.14.3) | protein | 326 | 51% helix, 17% strand | P07740 |
| B | Bacterial luciferase (EC 1.14.14.3) | protein | 320 | 48% helix, 17% strand | P07739 |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 474 | 0.80 | 0.87 | 44 | empty |
| 2 | 126 | 0.69 | 0.90 | 28 | empty |
| 3 | 348 | 0.68 | 0.81 | 54 | EDO |
| 4 | 69 | 0.60 | 0.90 | 24 | empty |
| 5 | 115 | 0.52 | 0.81 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 2137 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 1LUC · Bacterial luciferase · the same entry in another collection · chain A against A, TM-score 1.00
- P07739 · AlphaFold monomer V2.0 prediction for alkanal monooxygenase beta chain (P07739) · a predicted model of the same protein · chain B against A, TM-score 0.99
- P07740 · AlphaFold monomer V2.0 prediction for alkanal monooxygenase alpha chain (P07740) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07740
- Every structure of UniProt P07739
- Elsewhere: RCSB PDB 1LUC · PDBe 1LUC · UniProt P07740 · UniProt P07739
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