Research workbench
Crystal structure of hmp-1-hmp-2 complex
Analyse Crystal structure of hmp-1-hmp-2 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5XA5
- Type
- protein
- Length
- 275 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-catenin-like protein hmp-1; Beta-catenin-like protein hmp-2
- UniProt
- P90947, O44326
- Pockets
- 2 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 80% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-catenin-like protein hmp-1 | protein | 248 | 81% helix, 1% strand | P90947 |
| B | Beta-catenin-like protein hmp-2 | protein | 27 | 70% helix, 4% strand | O44326 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 213 | 0.56 | 0.79 | 27 | empty |
| 2 | 59 | 0.34 | 0.77 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1622 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 5XA5 · Crystal structure of HMP-1-HMP-2 complex · the same entry in another collection · chain A against A, TM-score 1.00
- P90947 · AlphaFold monomer V2.0 prediction for alpha-catenin-like protein hmp-1 (P90947) · a predicted model of the same protein · chain A against A, TM-score 0.97
- O44326 · AlphaFold monomer V2.0 prediction for beta-catenin-like protein hmp-2 (O44326) · a predicted model of the same protein · chain B against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P90947
- Every structure of UniProt O44326
- Elsewhere: RCSB PDB 5XA5 · PDBe 5XA5 · UniProt P90947 · UniProt O44326
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.