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5,10, methylene-tetrahydropholate DEHYDROGENASE/CYCLOHYDROLASE from E COLI.

Analyse 5,10, methylene-tetrahydropholate DEHYDROGENASE/CYCLOHYDROLASE from E COLI. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1B0A
Type: protein
Length: 287 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (fold bifunctional protein)
UniProt: P24186
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (fold bifunctional protein)	protein	287	41% helix, 15% strand	P24186

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	458	0.63	0.76	58	empty

Compared structures

1B0A · 5,10, methylene-tetrahydropholate DEHYDROGENASE/CYCLOHYDROLASE from E COLI. · the same entry in another collection · chain A against A, TM-score 1.00
P24186 · AlphaFold monomer V2.0 prediction for bifunctional protein fold (P24186) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P24186
Elsewhere: RCSB PDB 1B0A · PDBe 1B0A · UniProt P24186

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