Research workbench

3.5A resolution structure of a cobalt energy-coupling factor transporter using lcp method-cbimqo

Analyse 3.5A resolution structure of a cobalt energy-coupling factor transporter using… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5X41
Type: protein
Length: 1,959 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cobalt ABC transporter ATP-binding protein; Cobalt transport protein cbim…
UniProt: A0A0Q0R232
Pockets: 20 · best druggability 0.79

Structure

x-ray diffraction · 7 distinct chains · 49% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cobalt ABC transporter ATP-binding protein	protein	263	34% helix, 16% strand	—
B	Cobalt ABC transporter ATP-binding protein	protein	258	35% helix, 12% strand	—
M, E	Cobalt transport protein cbim	protein	207	70% helix, 0% strand	A0A0Q0R232
Q	Uncharacterized protein cbiq	protein	243	69% helix, 0% strand	—
C	Cobalt ABC transporter ATP-binding protein	protein	270	37% helix, 21% strand	—
D	Cobalt ABC transporter ATP-binding protein	protein	267	39% helix, 20% strand	—
F	Uncharacterized protein cbiq	protein	244	65% helix, 0% strand	—

Pockets

20 pockets found on a 1 Å grid, 17 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1160	0.79	0.81	93	empty
2	1067	0.79	0.81	88	empty
3	934	0.78	0.80	66	empty
4	968	0.78	0.80	91	empty
5	1048	0.76	0.78	101	empty

Interfaces

13 interfaces between chains.

E–F · 3134 Å² buried · 18 hydrogen bonds · protein-protein
M–Q · 3109 Å² buried · 11 hydrogen bonds · protein-protein
D–F · 1595 Å² buried · 20 hydrogen bonds · protein-protein
B–Q · 1574 Å² buried · 17 hydrogen bonds · protein-protein
C–F · 1005 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

5X41 · 3.5A resolution structure of a cobalt energy-coupling factor transporter using LCP… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0Q0R232
Elsewhere: RCSB PDB 5X41 · PDBe 5X41 · UniProt A0A0Q0R232

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.