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Crystal structure of chaetomium thermophilum UTP10 N-terminal domain in complex with UTP17 C-terminal helices
Analyse Crystal structure of chaetomium thermophilum UTP10 N-terminal domain in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5WYL
- Type
- protein
- Length
- 909 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative uncharacterized protein
- UniProt
- G0S5L1, G0SCS8
- Pockets
- 7 · best druggability 0.63
Structure
x-ray diffraction · 4 distinct chains · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative uncharacterized protein | protein | 411 | 74% helix, 0% strand | G0S5L1 |
| B | Putative uncharacterized protein | protein | 39 | 54% helix, 0% strand | G0SCS8 |
| C | Putative uncharacterized protein | protein | 418 | 75% helix, 0% strand | G0S5L1 |
| D | Putative uncharacterized protein | protein | 41 | 54% helix, 0% strand | G0SCS8 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 478 | 0.63 | 0.76 | 45 | empty |
| 2 | 326 | 0.60 | 0.78 | 33 | empty |
| 3 | 311 | 0.54 | 0.75 | 44 | empty |
| 4 | 111 | 0.37 | 0.74 | 24 | empty |
| 5 | 94 | 0.36 | 0.75 | 21 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1367 Ų buried · 8 hydrogen bonds · protein-protein
- C–D · 1363 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 659 Ų buried · 4 hydrogen bonds · protein-protein
- B–C · 112 Ų buried · 3 hydrogen bonds · protein-protein
- A–D · 97 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5WYL · Crystal structure of Chaetomium thermophilum Utp10 N-terminal domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G0S5L1
- Every structure of UniProt G0SCS8
- Elsewhere: RCSB PDB 5WYL · PDBe 5WYL · UniProt G0S5L1 · UniProt G0SCS8
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