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Crystal structure of TSR1

Analyse Crystal structure of TSR1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5WWN
Type: protein
Length: 531 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribosome biogenesis protein TSR1
UniProt: Q07381
Ligands: SO4
Pockets: 8 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 22% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribosome biogenesis protein TSR1	protein	531	22% helix, 37% strand	Q07381

Ligands and binding sites

SO4 · Sulfate ion · ion · 10 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	198	0.56	0.79	21	empty
2	88	0.53	0.84	24	empty
3	82	0.41	0.79	18	empty
4	131	0.40	0.74	21	empty
5	57	0.38	0.80	18	empty

Compared structures

5WWN · Crystal structure of Tsr1 · the same entry in another collection · chain A against A, TM-score 1.00
Q07381 · AlphaFold monomer V2.0 prediction for ribosome biogenesis protein TSR1 (Q07381) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q07381
Elsewhere: RCSB PDB 5WWN · PDBe 5WWN · UniProt Q07381

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