Chaperone spy bound to IM7 6-45 ensemble

Structure

x-ray diffraction · 3 distinct chains · 58% helix, 0% strand (DSSP).

Ligands and binding sites

• ZN · Zinc ion · metal · 8 copies · chains A, B
• CL · Chloride ion · ion · 2 copies · chains A, B
• IMD · Imidazole · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

3 interfaces between chains.

• A–B · 1673 Ų buried · 25 hydrogen bonds · protein-protein
• B–C · 110 Ų buried · 0 hydrogen bonds · protein-protein
• A–C · 82 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

• 5WNW · Chaperone Spy bound to Im7 6-45 ensemble · the same entry in another collection · chain A against A, TM-score 1.00
• P77754 · AlphaFold monomer V2.0 prediction for periplasmic chaperone spy (P77754) · a predicted model of the same protein · chain B against A, TM-score 0.78
• Q03708 · AlphaFold monomer V2.0 prediction for colicin-E7 immunity protein (Q03708) · a predicted model of the same protein · chain C against A, TM-score 0.20

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P77754
• Every structure of UniProt Q03708
• Elsewhere: RCSB PDB 5WNW · PDBe 5WNW · UniProt P77754 · UniProt Q03708