Research workbench
The atomic structure of adeno-associated virus (aav-2), a vector for human gene therapy
Analyse The atomic structure of adeno-associated virus (aav-2), a vector for human gene… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1LP3
- Type
- protein
- Length
- 519 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aav-2 capsid protein
- UniProt
- P03135
- Pockets
- 6 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aav-2 capsid protein | protein | 519 | 5% helix, 32% strand | P03135 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 648 | 0.66 | 0.75 | 61 | empty |
| 2 | 289 | 0.54 | 0.75 | 44 | empty |
| 3 | 119 | 0.45 | 0.78 | 23 | empty |
| 4 | 119 | 0.38 | 0.74 | 27 | empty |
| 5 | 56 | 0.35 | 0.79 | 19 | empty |
Compared structures
- 1LP3 · The Atomic Structure of Adeno-Associated Virus (AAV-2), a Vector for Human Gene Therapy · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03135
- Elsewhere: RCSB PDB 1LP3 · PDBe 1LP3 · UniProt P03135
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