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Crystal structure of legionella pneumophila effector LPG2328

Analyse Crystal structure of legionella pneumophila effector LPG2328 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5WD8
Type: protein
Length: 180 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LEM22
UniProt: G8UTY6
Pockets: 1 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 86% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LEM22	protein	90	86% helix, 0% strand	G8UTY6
B	LEM22	protein	90	87% helix, 0% strand	G8UTY6

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	162	0.69	0.88	23	empty

Interfaces

1 interface between chains.

A–B · 826 Å² buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

5WD8 · Crystal structure of Legionella pneumophila effector lpg2328 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G8UTY6
Elsewhere: RCSB PDB 5WD8 · PDBe 5WD8 · UniProt G8UTY6

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