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Designing higher resolution self-assembled 3D DNA crystals via strand terminus modifications

Analyse Designing higher resolution self-assembled 3D DNA crystals via strand terminus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5W6W
Type
DNA
Length
42 nucleotides
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'- D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)- 3'); DNA…

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'- D(*GP*AP*GP*CP*AP*GP*CP*CP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)- 3')dna21——
BDNA (5'-D(P*CP*CP*GP*TP*AP*CP*A)-3')dna7——
CDNA (5'-D(P*GP*GP*CP*TP*GP*CP*T)-3')dna7——
DDNA (5'-D(P*CP*TP*GP*AP*TP*GP*T)-3')dna7——

Interfaces

5 interfaces between chains.

  • A–B · 338 Ų buried · 29 hydrogen bonds · nucleic-nucleic
  • A–C · 335 Ų buried · 27 hydrogen bonds · nucleic-nucleic
  • A–D · 281 Ų buried · 23 hydrogen bonds · nucleic-nucleic
  • B–D · 99 Ų buried · 3 hydrogen bonds · nucleic-nucleic
  • B–C · 99 Ų buried · 0 hydrogen bonds · nucleic-nucleic

Compared structures

  • 5W6W · Designing Higher Resolution Self-Assembled 3D DNA Crystals via Strand Terminus… · the same entry in another collection · chain A against A, TM-score 1.00

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