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Solution structure of ets transcription factor PU.1

Analyse Solution structure of ets transcription factor PU.1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5W3G
Type: protein
Length: 110 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription factor PU.1
UniProt: P17433
Pockets: 3 · best druggability 0.45

Structure

solution nmr · 1 distinct chain · 36% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription factor PU.1	protein	110	36% helix, 13% strand	P17433

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	188	0.45	0.74	23	empty
2	60	0.34	0.77	15	empty
3	84	0.32	0.73	14	empty

Compared structures

5W3G · Solution Structure of ETS Transcription Factor PU.1 · the same entry in another collection · chain A against A, TM-score 1.00
P17433 · AlphaFold monomer V2.0 prediction for transcription factor PU.1 (P17433) · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17433
Elsewhere: RCSB PDB 5W3G · PDBe 5W3G · UniProt P17433

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