Research workbench
HCV NS5B RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor mk-8876
Analyse HCV NS5B RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5W2E
- Type
- protein
- Length
- 1,118 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P26663
- Ligands
- 9VY
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 559 | — | P26663 |
Ligands and binding sites
- 9VY · 2-(4-fluorophenyl)-5-(11-fluoro-6H-pyrido[2',3':5,6][1, 3]oxazino[3,4-a]indol-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5W2E · HCV NS5B RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor MK-8876 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26663
- Elsewhere: RCSB PDB 5W2E · PDBe 5W2E · UniProt P26663
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