Research workbench
Crystal structure of D-ribose-5-phosphate isomerase (rpia) from escherichia COLI.
Analyse Crystal structure of D-ribose-5-phosphate isomerase (rpia) from escherichia… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1LKZ
- Type
- protein
- Length
- 438 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribose 5-phosphate isomerase a
- EC
- 5.3.1.6
- UniProt
- P0A7Z0
- Pockets
- 6 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ribose 5-phosphate isomerase a (EC 5.3.1.6) | protein | 219 | 34% helix, 31% strand | P0A7Z0 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.46 | 0.78 | 21 | empty |
| 2 | 127 | 0.45 | 0.77 | 20 | empty |
| 3 | 73 | 0.38 | 0.79 | 17 | empty |
| 4 | 90 | 0.38 | 0.76 | 25 | empty |
| 5 | 74 | 0.37 | 0.78 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1164 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 14 modified (engineered).
Compared structures
- 1LKZ · Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli. · the same entry in another collection · chain A against A, TM-score 1.00
- P0A7Z0 · AlphaFold monomer V2.0 prediction for ribose-5-phosphate isomerase a (P0A7Z0) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A7Z0
- Elsewhere: RCSB PDB 1LKZ · PDBe 1LKZ · UniProt P0A7Z0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.