Research workbench
Crystal structure of influenza a virus matrix protein M1 (nls-88E, pH 6.2)
Analyse Crystal structure of influenza a virus matrix protein M1 (nls-88E, pH 6.2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5V7S
- Type
- protein
- Length
- 473 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Matrix protein 1
- UniProt
- P05777
- Ligands
- PO4
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 3 distinct chains · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Matrix protein 1 | protein | 164 | 71% helix, 0% strand | P05777 |
| B | Matrix protein 1 | protein | 154 | 69% helix, 0% strand | P05777 |
| C | Matrix protein 1 | protein | 155 | 70% helix, 0% strand | P05777 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 648 | 0.71 | 0.79 | 65 | empty |
| 2 | 127 | 0.60 | 0.85 | 23 | empty |
| 3 | 91 | 0.38 | 0.76 | 13 | empty |
Interfaces
3 interfaces between chains.
- B–C · 816 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 682 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 20 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 5V7S · Crystal structure of Influenza A virus matrix protein M1 (NLS-88E, pH 6.2) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05777
- Elsewhere: RCSB PDB 5V7S · PDBe 5V7S · UniProt P05777
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.