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Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective labelling of RNA (plor)

Analyse Adenine riboswitch aptamer domain labelled with iodo-uridine by… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5UZA
Type
RNA
Length
71 nucleotides
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (71-mer)
Ligands
ADE, MG
Pockets
2 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
XRNA (71-mer)rna71——

Ligands and binding sites

  • ADE · Adenine · ligand · chains X
  • MG · Magnesium ion · metal · 3 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18280.670.7536MG
22890.490.7425ADE, MG

Modifications

Observed in the structure: 2 modified (nucleotide modification).

Compared structures

  • 5UZA · Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective… · the same entry in another collection · chain X against X, TM-score 1.00

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