Research workbench
Type II DAH7PS from pseudomonas aeruginosa with TRP bound
Analyse Type II DAH7PS from pseudomonas aeruginosa with TRP bound in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5UXM
- Type
- protein
- Length
- 445 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- EC
- 2.5.1.54
- UniProt
- Q9I000
- Ligands
- PEP, TRP, CO, PO4, CL
- Pockets
- 2 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phospho-2-dehydro-3-deoxyheptonate aldolase (EC 2.5.1.54) | protein | 445 | 43% helix, 14% strand | Q9I000 |
Ligands and binding sites
- PEP · Phosphoenolpyruvate · ligand · chains A
- TRP · Tryptophan · ligand · chains A
- CO · Cobalt (II) ion · metal · chains A
- PO4 · Phosphate ion · ion · 2 copies · chains A
- CL · Chloride ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 247 | 0.65 | 0.83 | 41 | PEP, PO4 |
| 2 | 220 | 0.53 | 0.77 | 29 | TRP |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5UXM · Type II DAH7PS from Pseudomonas aeruginosa with Trp bound · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9I000
- Elsewhere: RCSB PDB 5UXM · PDBe 5UXM · UniProt Q9I000
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