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RNA hairpin structure containing 2-meimpg monomer analogue and 2- meimp-oligomer analogue

Analyse RNA hairpin structure containing 2-meimpg monomer analogue and 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5UX3
Type
RNA
Length
32 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (25-mer); RNA (5'-D(*(RG))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
Ligands
8OS

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA (25-mer)rna25——
BRNA (5'-D(*(RG))-R(P*CP*AP*CP*CP*UP*CP*A)-3')rna7——

Ligands and binding sites

  • 8OS · 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl) phosphoryl]guanosine · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 325 Ų buried · 29 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 3 modified, 1 covalent (nucleotide modification, covalent ligand).

Compared structures

  • 5UX3 · RNA hairpin structure containing 2-MeImpG monomer analogue and 2-MeImp-oligomer analogue · the same entry in another collection · chain A against A, TM-score 1.00

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