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Srta sortase from actinomyces oris

Analyse Srta sortase from actinomyces oris in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5UTT
Type: protein
Length: 720 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sortase
UniProt: A0A0X8K1J2
Ligands: CL
Pockets: 9 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Sortase	protein	180	8% helix, 37% strand	A0A0X8K1J2

Ligands and binding sites

CL · Chloride ion · ion · 12 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.58	0.88	23	empty
2	109	0.56	0.84	24	empty
3	213	0.51	0.76	34	CL
4	201	0.50	0.76	36	CL
5	95	0.40	0.77	19	empty

Interfaces

3 interfaces between chains.

C–D · 845 Å² buried · 14 hydrogen bonds · protein-protein
A–B · 813 Å² buried · 15 hydrogen bonds · protein-protein
A–C · 741 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

5UTT · SrtA sortase from Actinomyces oris · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0X8K1J2
Elsewhere: RCSB PDB 5UTT · PDBe 5UTT · UniProt A0A0X8K1J2

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