Research workbench
Crystal structure of heme-degrading protein RV3592 from mycobacterium tuberculosis - heme free with cleaved protein
Analyse Crystal structure of heme-degrading protein RV3592 from mycobacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5UQ4
- Type
- protein
- Length
- 176 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Monooxygenase
- UniProt
- I6X7R2
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Monooxygenase | protein | 86 | 24% helix, 44% strand | I6X7R2 |
| B | Monooxygenase | protein | 90 | 27% helix, 42% strand | I6X7R2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 142 | 0.57 | 0.83 | 26 | empty |
| 2 | 128 | 0.47 | 0.78 | 18 | empty |
| 3 | 102 | 0.46 | 0.79 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1493 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 5UQ4 · Crystal structure of Heme-Degrading Protein Rv3592 from Mycobacterium tuberculosis - heme… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I6X7R2
- Elsewhere: RCSB PDB 5UQ4 · PDBe 5UQ4 · UniProt I6X7R2
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