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Crystal structure of pyridoxal kinase from sheep brain
Analyse Crystal structure of pyridoxal kinase from sheep brain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1LHP
- Type
- protein
- Length
- 615 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pyridoxal kinase
- EC
- 2.7.1.35
- UniProt
- P82197
- Pockets
- 8 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyridoxal kinase (EC 2.7.1.35) | protein | 306 | 41% helix, 19% strand | P82197 |
| B | Pyridoxal kinase (EC 2.7.1.35) | protein | 309 | 41% helix, 19% strand | P82197 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.78 | 0.98 | 17 | empty |
| 2 | 456 | 0.72 | 0.82 | 43 | empty |
| 3 | 364 | 0.70 | 0.82 | 42 | empty |
| 4 | 105 | 0.62 | 0.88 | 20 | empty |
| 5 | 122 | 0.47 | 0.79 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 2126 Ų buried · 33 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P82197
- Elsewhere: RCSB PDB 1LHP · PDBe 1LHP · UniProt P82197
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