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The crystal structure of a laci-type transcription regulator from bifidobacterium animalis subsp. lactis dsm 10140

Analyse The crystal structure of a laci-type transcription regulator from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5UFH
Type
protein
Length
280 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Laci-type transcriptional regulator
UniProt
B8DV56
Ligands
NO3
Pockets
2 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALaci-type transcriptional regulatorprotein28041% helix, 18% strandB8DV56

Ligands and binding sites

  • NO3 · Nitrate ion · ion · 22 copies · chains A
  • GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13000.740.8632GOL, NO3
2570.290.7517NO3

Modifications

Observed in the structure: 13 modified (engineered, oxidation).

Compared structures

  • 5UFH · The crystal structure of a LacI-type transcription regulator from Bifidobacterium… · the same entry in another collection · chain A against A, TM-score 1.00

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