Research workbench
Neurospora crassa polysaccharide monooxygenase 2 resting state joint X-RAY/NEUTRON refinement
Analyse Neurospora crassa polysaccharide monooxygenase 2 resting state joint… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5TKI
- Type
- protein
- Length
- 446 residues
- Chains
- 2
- Method
- x-ray diffraction; neutron diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lytic polysaccharide monooxygenase
- UniProt
- Q8WZQ2
- Ligands
- NAG, CU
- Pockets
- 2 · best druggability 0.51
Structure
x-ray diffraction; neutron diffraction · 1 distinct chain · 6% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Lytic polysaccharide monooxygenase | protein | 223 | 6% helix, 35% strand | Q8WZQ2 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B
- CU · Copper (II) ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 139 | 0.51 | 0.80 | 18 | empty |
| 2 | 128 | 0.49 | 0.79 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 901 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide, 2 glycan (disulfide, N-glycosylation).
Compared structures
- 5TKI · Neurospora crassa polysaccharide monooxygenase 2 resting state joint X-ray/neutron… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WZQ2
- Elsewhere: RCSB PDB 5TKI · PDBe 5TKI · UniProt Q8WZQ2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.