Research workbench
Structure of the mind complex shows a regulatory focus of yeast kinetochore assembly
Analyse Structure of the mind complex shows a regulatory focus of yeast kinetochore… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5T58
- Type
- protein
- Length
- 820 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- KLLA0F02343P; KLLA0E05809P; KLLA0D15741P; KLLA0C15939P
- UniProt
- Q6CLK3, Q6CPD1, Q6CQN5, Q6CT27
- Pockets
- 18 · best druggability 0.81
Structure
x-ray diffraction · 4 distinct chains · 68% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | KLLA0F02343P | protein | 233 | 71% helix, 0% strand | Q6CLK3 |
| B | KLLA0E05809P | protein | 190 | 75% helix, 0% strand | Q6CPD1 |
| D | KLLA0D15741P | protein | 201 | 54% helix, 0% strand | Q6CQN5 |
| N | KLLA0C15939P | protein | 196 | 73% helix, 0% strand | Q6CT27 |
Pockets
18 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 205 | 0.81 | 0.94 | 31 | empty |
| 2 | 183 | 0.62 | 0.83 | 32 | empty |
| 3 | 402 | 0.62 | 0.77 | 44 | empty |
| 4 | 113 | 0.59 | 0.85 | 20 | empty |
| 5 | 126 | 0.57 | 0.84 | 27 | empty |
Interfaces
6 interfaces between chains.
- A–B · 4257 Ų buried · 28 hydrogen bonds · protein-protein
- D–N · 3975 Ų buried · 17 hydrogen bonds · protein-protein
- A–N · 1726 Ų buried · 9 hydrogen bonds · protein-protein
- A–D · 1267 Ų buried · 2 hydrogen bonds · protein-protein
- B–D · 978 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5T58 · Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly · the same entry in another collection · chain N against N, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6CLK3
- Every structure of UniProt Q6CPD1
- Every structure of UniProt Q6CQN5
- Every structure of UniProt Q6CT27
- Elsewhere: RCSB PDB 5T58 · PDBe 5T58 · UniProt Q6CLK3 · UniProt Q6CPD1 · UniProt Q6CQN5 · UniProt Q6CT27
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