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Structural genomics, crystal structure of cephalosporin C deacetylase

Analyse Structural genomics, crystal structure of cephalosporin C deacetylase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1L7A
Type: protein
Length: 636 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cephalosporin C deacetylase
EC: 3.1.1.41
UniProt: P94388
Pockets: 2 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Cephalosporin C deacetylase (EC 3.1.1.41)	protein	318	38% helix, 20% strand	P94388

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1017	0.75	0.78	83	empty
2	133	0.41	0.75	26	empty

Interfaces

1 interface between chains.

A–B · 943 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

1L7A · structural Genomics, crystal structure of Cephalosporin C deacetylase · the same entry in another collection · chain A against A, TM-score 1.00
P94388 · AlphaFold monomer V2.0 prediction for cephalosporin-C deacetylase (P94388) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P94388
Elsewhere: RCSB PDB 1L7A · PDBe 1L7A · UniProt P94388

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