Research workbench

Crystal structure of a parasite protein

Analyse Crystal structure of a parasite protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1KZQ
Type: protein
Length: 506 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major surface antigen P30
UniProt: P13664
Pockets: 3 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Major surface antigen P30	protein	253	8% helix, 41% strand	P13664

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	601	0.64	0.75	69	empty
2	246	0.57	0.78	27	empty
3	128	0.44	0.77	25	empty

Interfaces

1 interface between chains.

A–B · 1058 Å² buried · 24 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 disulfide (disulfide).

Compared structures

1KZQ · crystal structure of a parasite protein · the same entry in another collection · chain A against A, TM-score 1.00
P13664 · AlphaFold monomer V2.0 prediction for major surface antigen P30 (P13664) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13664
Elsewhere: RCSB PDB 1KZQ · PDBe 1KZQ · UniProt P13664

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.