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Sacbrood virus of honeybee

Analyse Sacbrood virus of honeybee in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
5OYP
Type
protein
Length
781 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Structural protein VP1; Structural protein VP2; Structural protein VP3; Minor capsid…
UniProt
A0A223DN69, Q6ITS8, Q9IGK7
Pockets
10 · best druggability 0.66

Structure

electron microscopy · 4 distinct chains · 10% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AStructural protein VP1protein24313% helix, 34% strandA0A223DN69
BStructural protein VP2protein23911% helix, 42% strandQ6ITS8
CStructural protein VP3protein2737% helix, 30% strandA0A223DN69
DMinor capsid protein micpprotein260% helix, 8% strandQ9IGK7

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13930.660.8038empty
2530.600.9215empty
3590.510.8718empty
4910.450.8019empty
51410.440.7618empty

Interfaces

6 interfaces between chains.

  • A–C · 5526 Ų buried · 59 hydrogen bonds · protein-protein
  • A–B · 1430 Ų buried · 25 hydrogen bonds · protein-protein
  • B–C · 1363 Ų buried · 25 hydrogen bonds · protein-protein
  • B–D · 668 Ų buried · 8 hydrogen bonds · protein-protein
  • A–D · 363 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

  • 5OYP · Sacbrood virus of honeybee · the same entry in another collection · chain A against A, TM-score 1.00

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