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Crystal structure of STAT2 in complex with IRF9
Analyse Crystal structure of STAT2 in complex with IRF9 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5OEN
- Type
- protein
- Length
- 336 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Interferon regulatory factor 9; Signal transducer and activator of transcription
- UniProt
- Q61179, Q3UDU1
- Pockets
- 2 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 51% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Interferon regulatory factor 9 | protein | 165 | 15% helix, 37% strand | Q61179 |
| B | Signal transducer and activator of transcription | protein | 171 | 87% helix, 0% strand | Q3UDU1 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.32 | 0.76 | 18 | empty |
| 2 | 69 | 0.31 | 0.74 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1118 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q61179
- Every structure of UniProt Q3UDU1
- Elsewhere: RCSB PDB 5OEN · PDBe 5OEN · UniProt Q61179 · UniProt Q3UDU1
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